EFFECTS OF BRUGIA PAHANGI INFECTION ON THE CARDIOVASCULAR SYSTEM OF STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RATS

E. Kimura; Y. Fujimaki; M. Niwa; M. Fujiwara; T. Kadosaka

doi:10.1645/0022-3395(2002)088[0839:EOBPIO]2.0.CO;2

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E. Kimura,¹ Y. Fujimaki,^1,* M. Niwa,^1,** M. Fujiwara,¹ T. Kadosaka¹

¹Department of Parasitology, Aichi Medical University, Nagakute, Aichi-ken, 480-1195 Japan. kim

^** Institute of Tropical Medicine, Nagasaki University, Nagasaki 852-8523, Japan.
^**† 1st Department of Pharmacology, Nagasaki University School of Medicine, Nagasaki 852-8523, Japan.

Abstract

To determine if filarial infection causes any effect on the cardiovascular system of the host animal, stroke-prone spontaneously hypertensive rats were infected with Brugia pahangi under the assumption that these rats would reveal pathological changes more clearly and in a shorter period than would ordinary rats. The infection resulted in loss of body weight, increase in heart weight, enlargement of left ventricle, and higher mortality rate.

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E. Kimura, Y. Fujimaki, M. Niwa, M. Fujiwara, and T. Kadosaka "EFFECTS OF BRUGIA PAHANGI INFECTION ON THE CARDIOVASCULAR SYSTEM OF STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RATS," Journal of Parasitology 88(5), 839-842, (1 October 2002). https://doi.org/10.1645/0022-3395(2002)088[0839:EOBPIO]2.0.CO;2

Received: 2 January 2002; Accepted: 1 April 2002; Published: 1 October 2002

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